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This book constitutes the refereed proceedings of the 14th International Conference on Computational Methods in Systems Biology, CMSB 2016, held in Cambridge, UK, in September 2016. The 20 full papers, 3 tool papers and 9 posters presented were carefully reviewed and selected from 37 regular paper submissions. The topics include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; and computational approaches for synthetic biology.

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Modeling biological processes.- Models and their biological applications.- Frameworks for model verification, validation, analysis, and simulation of biological systems.- High-performance computational systems biology and parallel implementations.- Model inference from experimental data.- Model integration from biological databases.- Multi-scale modeling and analysis methods.- Computational approaches for synthetic biology.

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