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Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients.

Liver Anesthesiology and Critical Care Medicine , 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.

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Section I: Physiology, Pathophysiology and Pharmacology of Liver Disease

Physiology and anatomy of the liver
Chronic liver failure and hepatic cirrhosis
The splanchnic and systemic circulation in liver disease
Drug metabolism in liver failure
Evaluation of liver function and injury

Section II: Anesthesiology for Liver Transplantation.

History of liver transplantation
Recipient and donor selection and transplant logistics: the European perspective
Recipient and donor selection and transplant logistics: the US perspective
Preoperative risk assessment
Surgical techniques of liver transplantation
Intra-operative monitoring
Anesthetic techniques and practice patterns
Caval crossclamping, piggy-bag & veno-venous bypass
14. Hemodynamic manag ement and use of vasopressors
15. Coagulopathy: pathophysiology, evaluation & treatment
Massive blood loss and blood transfusion
Organ protection & the marginal donor / recipient
Pediatric liver transplantation
Combined Transplants: Liver / -heart / -kidney / -lung transplantation
The patient with a high MELD
Acute liver failure The patient with renal failure undergoing liver transplantation
The patient with cardiac disease
Pulmonary disease & hepatopulmonary syndrome
Neurological disease and increased intracranial pressure

Section III: Anesthesiology for Liver Surgery.

Types of liver surgery and indications
Anesthetic management, monitoring, fluids & electrolytes
Anesthetic aspects of the living donor hepatectomy
Analgesia for l iver resection including regional techniques
Complications of liver surgery
The patient with liver disease undergoing non-hepatic surgery
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Section IV: Critical Care Medicine for Liver transplantation.

Routine postoperative care
Immunosuppression
Acute kidney injury
Early graft failure
Sepsis and infection
Respiratory failure and ARDS Pain management

Section V: Critical care Medicine for Liver surgery.

The living related liver donor
Early complications: Liver failure, bile leak and sepsis

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Gebhard Wagener, MD is Associate Professor of Anesthesiology at Columbia University Medical Center, Director, Vascular Anesthesia Division, Member Division of Critical Care Anesthesia

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